Hey Lawson! I'm an FSA for Virt working in the field with Everpure customers on this exact thing. Largely, most customers I work with are going VMFS. For the customers that liked the "per-vm" monitoring vVols gave in vCenter, some are choosing NFS with our VAAI VIB installed on the ESXi hosts with AutoDir enabled. This gives you a managed directory for each VM and shows monitoring graphs per VM.
Many customers are using vVols for DB clone refresh processes, in which customers are usually going with a combo of VMFS for the OS drives and RDM's for the data drives. There are alternatives to do entirely VMFS, but it will require more lines of scripting to fully refresh those drives. There are some code examples on the github page here:
https://github.com/PureStorage-OpenConnect
